Prime Highlights
- Women with cardiovascular disease postmenopause have a 31% higher risk of developing breast cancer for every 5 kg/m² increase in BMI.
- The study suggests that inclusion of control of weight in the prevention of breast cancer among women at high risk be included.
Key Fact
- Overweight women with cardiovascular disease can add 153 extra cases of breast cancer per 100,000 annually.
- Diabetes makes little contribution to the risk of breast cancer linked with BMI.
Key Background
A large- scale new study set up that postmenopausal women who have cardiovascular complaint( CVD) are significantly more likely to develop bone cancer if, in addition, they’ve a advanced body mass indicator( BMI). The study was conducted in the CANCER journal of the American Cancer Society and targets the double threat of rotundity, particularly in women who formerly have cardiovascular complaint.
Researchers analyzed medical records on over 168,000 British and European women who were free of cardiovascular disease or diabetes at recruitment. They identified a total of close to 6,800 breast cancers with a mean follow-up period of about 11 years. This was found upon investigation to be a large difference in breast cancer risk: with 31% increased risk in the women who eventually developed CVD per 5 kg/m² increase in BMI, and increased risk by 13% in the women who did not develop CVD.
In contrast to predictions, either the development or failure to develop type 2 diabetes in a woman did not have an apparent impact on breast cancer risk according to BMI. This indicates that obesity itself plays a direct and independent part to render women vulnerable to breast cancer irrespective of diabetes.
Overweight and obese women (≥ 25 BMI) with cardiovascular disease were estimated to have an additional 153 cases of breast cancer per 100,000 women annually. This puts into perspective the importance of considering BMI and cardiovascular disease in formulating screening and prevention policy for cancer. Researchers estimate that enrolling high-risk women in weight loss clinical trials and cancer prevention trials could prevent onset and improve outcomes.
Overall, this study suggests that there is a demand for obesity health programs incorporated to maximize cardiovascular health and reduce cancer risk in older women. Specialist prevention programs may be a starting point on the road to better future health for this vulnerable group.
