Prime Highlights
- Sinai Hospital has begun using AI-powered tool Sepsis ImmunoScore for early sepsis detection.
- The tool analyses 22 parameters to identify sepsis patterns within 24 hours.
Key Facts
- LifeBridge Health operates five hospitals and care facilities across Maryland.
- The tool received first-of-its-kind US regulatory authorisation for sepsis diagnosis in 2024.
Background
The Sinai Hospital of Baltimore, which is part of LifeBridge Health, has started using the AI diagnostic system for detecting sepsis.
Prenosis, a Chicago-based technology startup, created this diagnostic tool called Sepsis ImmunoScore. This technology uses 22 different biological markers to detect patterns in the immune system of the patient. The technology received US regulatory authorisation in 2024, becoming the first AI-based software cleared to help diagnose the condition.
A study published in a medical journal earlier this year found the tool showed strong accuracy in diagnosing sepsis while also helping predict related outcomes such as mortality risk, length of hospitalization and the requirement for critical care.
Sinai Hospital was among several research centres nationwide that contributed patient data used to train and validate the tool. Hospital officials said the move reflects years of collaboration between researchers and the technology company, allowing findings from earlier studies to be applied directly in clinical settings.
Sepsis remains one of the most challenging conditions to diagnose, often requiring extended monitoring and testing before doctors can confirm an infection in the bloodstream. Delays in identifying the condition can worsen outcomes, while uncertainty can also lead to overtreatment or missed diagnoses.
Officials at Prenosis said the tool takes under an hour to deliver results after testing begins, offering clinicians early insight into a patient’s risk level. The company added that it is also working on personalised treatment approaches based on individual immune profiles.
Since introducing the tool six weeks ago, the hospital has used it to evaluate 75 patients, with plans to expand its use across LifeBridge Health’s broader hospital network.
